טוען...

Age- and genotype-dependent variability in the protein abundance and activity of six major uridine diphosphate-glucuronosyltransferases in human liver

The ontogeny of hepatic uridine diphosphate-glucuronosyltransferases (UGTs) was investigated by LC-MS/MS proteomics to determine UGT protein abundance in human liver microsomes isolated from 136 pediatric (0–18 years) and 35 adult (age 18–67 years) donors. Microsomal protein abundances of UGT1A1, UG...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Clin Pharmacol Ther
Main Authors: Bhatt, Deepak Kumar, Mehrotra, Aanchal, Gaedigk, Andrea, Chapa, Revathi, Basit, Abdul, Zhang, Haeyoung, Choudhari, Prachi, Boberg, Mikael, Pearce, Robin E., Gaedigk, Roger, Broeckel, Ulrich, Leeder, J. Steven, Prasad, Bhagwat
פורמט: Artigo
שפה:Inglês
יצא לאור: 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222000/
https://ncbi.nlm.nih.gov/pubmed/29737521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1109
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