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RDNA-04. POTENTIAL MECHANISM OF TEMOZOLOMIDE-MEDIATED RADIO-SENSITIZATION IN MGMT HYPERMETHYLATED GLIOBLASTOMA CELLS

Temozolomide (TMZ) mediated radio-sensitization is preferentially observed in MGMT hypermethylated glioblastoma (GBM) and is modulated by unknown underlying mechanisms. To gain insight into the potential mechanism of TMZ-induced radio-sensitization, we examined the effect of TMZ pre-exposure on the...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kitange, Gaspar, Smith, Emily, Gupta, Shiv, Sarkaria, Jann
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217520/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.920
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