GENE-20. A NOVEL K-M ENHANCER REGULATES TEMOZOLOMIDE RESISTANCE AND TUMOR GROWTH IN GLIOBLASTOMA

Emergence of temozolomide (TMZ) resistance and increased tumor aggressiveness are common in recurrent glioblastoma. However, mechanisms promoting these phenomena are incompletely understood. Previously, we described in vivo models of acquired TMZ resistance in GBM patient derived xenografts (PDXs),...

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Publicado en:Neuro Oncol
Main Authors: Chen, Xiaoyue, Zhang, Minjie, Gan, Haiyun, Lee, Jeong-Heon, Fang, Dong, Kitange, Gaspar, He, Lihong, Hu, Zeng, Zhang, Zhiguo, Sarkaria, Jann
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216651/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.446
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