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TMOD-19. MUTANT IDH1 PROMOTES GLIOMA FORMATION IN VIVO

Gliomas are the most common primary central nervous system tumor but the molecular mechanisms responsible for their development and progression are not completely understood. Isocitrate dehydrogenase 1 (IDH1) is the most commonly mutated gene in grade II-III glioma and secondary glioblastoma (GBM) b...

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Publicat a:Neuro Oncol
Autors principals: Yu, Diana, Boekholder, Ryan, VanBrocklin, Matthew, Sonnen, Joshua, Colman, Howard, Holmen, Sheri
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216632/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1131
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