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TMOD-32. SUPPRESSION OF MUTANT BRAF EXPRESSION RESULTS IN GLIOMA REGRESSION AND INCREASED SURVIVAL IN VIVO
Activating mutations in BRAF have been identified in a significant number of human cancers including both pediatric and adult gliomas of varying grades. Specifically, the BRAFV600E mutation, which is the most common mutational variant, has been found in ~27% of pediatric anaplastic astrocytoma (WHO...
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Publicado no: | Neuro Oncol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692774/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1069 |
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