TMOD-32. SUPPRESSION OF MUTANT BRAF EXPRESSION RESULTS IN GLIOMA REGRESSION AND INCREASED SURVIVAL IN VIVO

Activating mutations in BRAF have been identified in a significant number of human cancers including both pediatric and adult gliomas of varying grades. Specifically, the BRAFV600E mutation, which is the most common mutational variant, has been found in ~27% of pediatric anaplastic astrocytoma (WHO...

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發表在:Neuro Oncol
Main Authors: Yu, Diana, Shin, Clifford, Robinson, James, Sommer, Danika, Welker, Adam, Holmen, Sheri
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692774/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1069
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