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TMOD-19. MUTANT IDH1 PROMOTES GLIOMA FORMATION IN VIVO

Gliomas are the most common primary central nervous system tumor but the molecular mechanisms responsible for their development and progression are not completely understood. Isocitrate dehydrogenase 1 (IDH1) is the most commonly mutated gene in grade II-III glioma and secondary glioblastoma (GBM) b...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Yu, Diana, Boekholder, Ryan, VanBrocklin, Matthew, Sonnen, Joshua, Colman, Howard, Holmen, Sheri
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216632/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1131
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