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Resistance to Enediyne Antitumor Antibiotics by Sequestration
The enediynes, microbial natural products with extraordinary cytotoxicities, have been translated into clinical drugs. Two self-resistance mechanisms are known in the enediyne producers—apoproteins for the nine-membered enediynes and self-sacrifice proteins for the ten-membered enediyne calicheamici...
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| Publicado no: | Cell Chem Biol |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6208323/ https://ncbi.nlm.nih.gov/pubmed/29937405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.05.012 |
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