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Resistance to Enediyne Antitumor Antibiotics by Sequestration
The enediynes, microbial natural products with extraordinary cytotoxicities, have been translated into clinical drugs. Two self-resistance mechanisms are known in the enediyne producers—apoproteins for the nine-membered enediynes and self-sacrifice proteins for the ten-membered enediyne calicheamici...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Chem Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6208323/ https://ncbi.nlm.nih.gov/pubmed/29937405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.05.012 |
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