Improved physical stability and aerosolization of inhalable amorphous ciprofloxacin powder formulations by incorporating synergistic colistin

OBJECTIVE: This study aimed to develop dry powder inhaler (DPI) combination formulations of ciprofloxacin and colistin for use in respiratory infections. Effects of colistin on physical stability and aerosolization of spray-dried ciprofloxacin were examined. METHODS: The combination DPI formulations...

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Dettagli Bibliografici
Pubblicato in:Mol Pharm
Autori principali: Shetty, Nivedita, Ahn, Patricia, Park, Heejun, Bhujbal, Sonal, Zemlyanov, Dmitry, Cavallaro, Alex, Mangal, Sharad, Li, Jian, Zhou, Qi (Tony)
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205724/
https://ncbi.nlm.nih.gov/pubmed/30028947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b00445
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