Influence of excipients on physical and aerosolization stability of spray dried high-dose powder formulations for inhalation

The aim of this study is to investigate the influence of excipients on physical and aerosolization stability of spray dried Ciprofloxacin dry powder inhaler formulations. The model drug, Ciprofloxacin hydrochloride, was co-spray dried with excipients such as disaccharides (sucrose, lactose, trehalos...

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Bibliographic Details
Published in:Int J Pharm
Main Authors: Shetty, Nivedita, Park, Heejun, Zemlyanov, Dmitry, Mangal, Sharad, Bhujbal, Sonal, Zhou, Qi (Tony)
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959799/
https://ncbi.nlm.nih.gov/pubmed/29678544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2018.04.034
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