Influence of excipients on physical and aerosolization stability of spray dried high-dose powder formulations for inhalation

The aim of this study is to investigate the influence of excipients on physical and aerosolization stability of spray dried Ciprofloxacin dry powder inhaler formulations. The model drug, Ciprofloxacin hydrochloride, was co-spray dried with excipients such as disaccharides (sucrose, lactose, trehalos...

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Veröffentlicht in:Int J Pharm
Hauptverfasser: Shetty, Nivedita, Park, Heejun, Zemlyanov, Dmitry, Mangal, Sharad, Bhujbal, Sonal, Zhou, Qi (Tony)
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959799/
https://ncbi.nlm.nih.gov/pubmed/29678544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2018.04.034
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