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Influence of excipients on physical and aerosolization stability of spray dried high-dose powder formulations for inhalation

The aim of this study is to investigate the influence of excipients on physical and aerosolization stability of spray dried Ciprofloxacin dry powder inhaler formulations. The model drug, Ciprofloxacin hydrochloride, was co-spray dried with excipients such as disaccharides (sucrose, lactose, trehalos...

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Detalhes bibliográficos
Publicado no:Int J Pharm
Main Authors: Shetty, Nivedita, Park, Heejun, Zemlyanov, Dmitry, Mangal, Sharad, Bhujbal, Sonal, Zhou, Qi (Tony)
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959799/
https://ncbi.nlm.nih.gov/pubmed/29678544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2018.04.034
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