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Correlations between surface composition and aerosolization of jet-milled dry powder inhaler formulations with pharmaceutical lubricants

Co-jet-milling drugs and lubricants may enable simultaneous particle size reduction and surface coating to achieve satisfactory aerosolization performance. This study aims to establish the relationship between surface lubricant coverage and aerosolization behavior of a model drug (ciprofloxacin HCl)...

詳細記述

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書誌詳細
出版年:Int J Pharm
主要な著者: Mangal, Sharad, Park, Heejun, Nour, Reham, Shetty, Nivedita, Cavallaro, Alex, Zemlyanov, Dmitry, Thalberg, Kyrre, Puri, Vibha, Nicholas, Mark, Narang, Ajit S., Zhou, Qi (Tony)
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708472/
https://ncbi.nlm.nih.gov/pubmed/31299339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2019.118504
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