Correlations between surface composition and aerosolization of jet-milled dry powder inhaler formulations with pharmaceutical lubricants

Co-jet-milling drugs and lubricants may enable simultaneous particle size reduction and surface coating to achieve satisfactory aerosolization performance. This study aims to establish the relationship between surface lubricant coverage and aerosolization behavior of a model drug (ciprofloxacin HCl)...

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Bibliographic Details
Published in:Int J Pharm
Main Authors: Mangal, Sharad, Park, Heejun, Nour, Reham, Shetty, Nivedita, Cavallaro, Alex, Zemlyanov, Dmitry, Thalberg, Kyrre, Puri, Vibha, Nicholas, Mark, Narang, Ajit S., Zhou, Qi (Tony)
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708472/
https://ncbi.nlm.nih.gov/pubmed/31299339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2019.118504
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