Simultaneous particle size reduction and homogeneous mixing to produce combinational powder formulations for inhalation by the single-step co-jet-milling

Homogeneous mixing of two cohesive jet-milled drug powders is a challenge for pharmaceutical manufacturing because of their cohesive nature resulting in the formation of strong and random agglomerates. In this study, colistin and ciprofloxacin were co-jet-milled to develop combinational antibiotic d...

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Bibliografiske detaljer
Udgivet i:	J Pharm Sci
Main Authors:	Ling, Junhong, Mangal, Sharad, Park, Heejun, Wang, Shaoning, Cavallaro, Alex, Zhou, Qi (Tony)
Format:	Artigo
Sprog:	Inglês
Udgivet:	2019
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6708488/ https://ncbi.nlm.nih.gov/pubmed/31112716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2019.05.011
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Simultaneous particle size reduction and homogeneous mixing to produce combinational powder formulations for inhalation by the single-step co-jet-milling

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