Composite particle formulations of colistin and meropenem with improved in-vitro bacterial killing and aerosolization for inhalation

Antibiotic combination therapy is promising for the treatment of lower respiratory tract infections caused by multi-drug resistant Gram-negative pathogens. Inhaled antibiotic therapy offers the advantage of direct delivery of the drugs to the site of infection, as compared to the parenteral administ...

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Publicado en:Int J Pharm
Autores principales: Mangal, Sharad, Park, Heejun, Zeng, Lingfei, Yu, Heidi H., Lin, Yu-wei, Velkov, Tony, Denman, John A., Zemlyanov, Dmitry, Li, Jian, Zhou, Qi (Tony)
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6086597/
https://ncbi.nlm.nih.gov/pubmed/30008433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2018.07.010
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