Effects of Moisture-Induced Crystallization on the Aerosol Performance of Spray Dried Amorphous Ciprofloxacin Powder Formulations

PURPOSE: This study aims to investigate the influence of different storage humidity conditions on crystallization and aerosol performance of inhalable spray dried amorphous powder formulations (Ciprofloxacin hydrochloride as the model drug). METHODS: The spray dried samples were stored at 20%, 55% a...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Shetty, Nivedita, Zeng, Lingfei, Mangal, Sharad, Nie, Haichen, Rowles, Matthew R., Guo, Rui, Han, Youngwoo, Park, Joon Hyeong, Zhou, Qi (Tony)
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942560/
https://ncbi.nlm.nih.gov/pubmed/29294198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2281-5
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