Deficiency of aldose reductase exacerbates early pressure overload-induced cardiac dysfunction and autophagy in mice

Pathological cardiac hypertrophy is associated with the accumulation of lipid peroxidation-derived aldehydes such as 4-hydroxy-trans-2-nonenal (HNE) and acrolein in the heart. These aldehydes are metabolized via several pathways, of which aldose reductase (AR) represents a broad-specificity route fo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Mol Cell Cardiol
Päätekijät: Baba, Shahid P., Zhang, Deqing, Singh, Mahavir, Dassanayaka, Sujith, Xie, Zhengzhi, Jagatheesan, Ganapathy, Zhao, Jingjing, Schmidtke, Virginia K, Brittian, Kenneth R., Merchant, Michael L., Conklin, Daniel J., Jones, Steven P., Bhatnagar, Aruni
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205513/
https://ncbi.nlm.nih.gov/pubmed/29627295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.04.002
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia