Deficiency of aldose reductase exacerbates early pressure overload-induced cardiac dysfunction and autophagy in mice

Pathological cardiac hypertrophy is associated with the accumulation of lipid peroxidation-derived aldehydes such as 4-hydroxy-trans-2-nonenal (HNE) and acrolein in the heart. These aldehydes are metabolized via several pathways, of which aldose reductase (AR) represents a broad-specificity route fo...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Mol Cell Cardiol
Hoofdauteurs: Baba, Shahid P., Zhang, Deqing, Singh, Mahavir, Dassanayaka, Sujith, Xie, Zhengzhi, Jagatheesan, Ganapathy, Zhao, Jingjing, Schmidtke, Virginia K, Brittian, Kenneth R., Merchant, Michael L., Conklin, Daniel J., Jones, Steven P., Bhatnagar, Aruni
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205513/
https://ncbi.nlm.nih.gov/pubmed/29627295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.04.002
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items