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Postischemic Deactivation of Cardiac Aldose Reductase: ROLE OF GLUTATHIONE S-TRANSFERASE P AND GLUTAREDOXIN IN REGENERATION OF REDUCED THIOLS FROM SULFENIC ACIDS

Aldose reductase (AR) is a multifunctional enzyme that catalyzes the reduction of glucose and lipid peroxidation-derived aldehydes. During myocardial ischemia, the activity of AR is increased due to the oxidation of its cysteine residues to sulfenic acids. It is not known, however, whether the activ...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wetzelberger, Karin, Baba, Shahid P., Thirunavukkarasu, Mahesh, Ho, Ye-Shih, Maulik, Nilanjana, Barski, Oleg A., Conklin, Daniel J., Bhatnagar, Aruni
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924019/
https://ncbi.nlm.nih.gov/pubmed/20538586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146423
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