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Posttranslational glutathiolation of aldose reductase (AKR1B1); a possible mechanism of protein recovery from S-nitrosylation
Nitric oxide (NO) is an important regulator of the catalytic activity of aldose reductase (AR). It reacts with the active site cysteines of AR and this reaction results in the formation of several kinetically distinct forms of the protein. The catalytic activity of AR is increased in the ischemic he...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929757/ https://ncbi.nlm.nih.gov/pubmed/19061876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2008.11.007 |
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