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Aldose reductase (AKR1B) deficiency promotes phagocytosis in bone marrow derived mouse macrophages

Macrophages are critical drivers of the immune response during infection and inflammation. The pathogenesis of several inflammatory conditions, such as diabetes, cancer and sepsis has been linked with aldose reductase (AR), a member of the aldo-keto reductase (AKR) superfamily. However, the role of...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Main Authors: Singh, Mahavir, Kapoor, Aniruddh, McCracken, James, Hill, Bradford, Bhatnagar, Aruni
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505634/
https://ncbi.nlm.nih.gov/pubmed/28111134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2017.01.012
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