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Aldose reductase (AKR1B) deficiency promotes phagocytosis in bone marrow derived mouse macrophages

Macrophages are critical drivers of the immune response during infection and inflammation. The pathogenesis of several inflammatory conditions, such as diabetes, cancer and sepsis has been linked with aldose reductase (AR), a member of the aldo-keto reductase (AKR) superfamily. However, the role of...

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Опубликовано в: :Chem Biol Interact
Главные авторы: Singh, Mahavir, Kapoor, Aniruddh, McCracken, James, Hill, Bradford, Bhatnagar, Aruni
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505634/
https://ncbi.nlm.nih.gov/pubmed/28111134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2017.01.012
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