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Role of Nitric Oxide in Regulating Aldose Reductase Activation in the Ischemic Heart

Aldose reductase (AR) catalyzes the reduction of several aldehydes ranging from lipid peroxidation products to glucose. The activity of AR is increased in the ischemic heart due to oxidation of its cysteine residues, but the underlying mechanisms remain unclear. To examine signaling mechanisms regul...

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Detalhes bibliográficos
Main Authors: Kaiserova, Karin, Tang, Xian-Liang, Srivastava, Sanjay, Bhatnagar, Aruni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431016/
https://ncbi.nlm.nih.gov/pubmed/18223294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709671200
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