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Role of Nitric Oxide in Regulating Aldose Reductase Activation in the Ischemic Heart

Aldose reductase (AR) catalyzes the reduction of several aldehydes ranging from lipid peroxidation products to glucose. The activity of AR is increased in the ischemic heart due to oxidation of its cysteine residues, but the underlying mechanisms remain unclear. To examine signaling mechanisms regul...

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Détails bibliographiques
Auteurs principaux: Kaiserova, Karin, Tang, Xian-Liang, Srivastava, Sanjay, Bhatnagar, Aruni
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431016/
https://ncbi.nlm.nih.gov/pubmed/18223294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709671200
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