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ALDOSE REDUCTASE PROTECTS AGAINST EARLY ATHEROSCLEROTIC LESION FORMATION IN APO E - NULL MICE

RATIONALE: Atherosclerotic lesion formation is associated with the accumulation of oxidized lipids. Products of lipid oxidation, particularly aldehydes, stimulate cytokine production and enhance monocyte adhesion, however their contribution to atherosclerotic lesion formation remains unclear. OBJECT...

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Detalhes bibliográficos
Main Authors: Srivastava, Sanjay, Vladykovskaya, Elena, Barski, Oleg A., Spite, Matthew, Kaiserova, Karin, Petrash, J. Mark, Chung, Stephen S, Hunt, Greg, Dawn, Buddhadeb, Bhatnagar, Aruni
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548455/
https://ncbi.nlm.nih.gov/pubmed/19729598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.200568
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