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Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes

Phospholipid oxidation generates several bioactive aldehydes that remain esterified to the glycerol backbone (‘core’ aldehydes). These aldehydes induce endothelial cells to produce monocyte chemotactic factors and enhance monocyte–endothelium adhesion. They also serve as ligands of scavenger recepto...

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Detalhes bibliográficos
Main Authors: Spite, Matthew, Baba, Shahid P., Ahmed, Yonis, Barski, Oleg A., Nijhawan, Kanchan, Petrash, J. Mark, Bhatnagar, Aruni, Srivastava, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925154/
https://ncbi.nlm.nih.gov/pubmed/17381426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061743
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