Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes

Phospholipid oxidation generates several bioactive aldehydes that remain esterified to the glycerol backbone (‘core’ aldehydes). These aldehydes induce endothelial cells to produce monocyte chemotactic factors and enhance monocyte–endothelium adhesion. They also serve as ligands of scavenger recepto...

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Autori principali: Spite, Matthew, Baba, Shahid P., Ahmed, Yonis, Barski, Oleg A., Nijhawan, Kanchan, Petrash, J. Mark, Bhatnagar, Aruni, Srivastava, Sanjay
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925154/
https://ncbi.nlm.nih.gov/pubmed/17381426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061743
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