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Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes

Phospholipid oxidation generates several bioactive aldehydes that remain esterified to the glycerol backbone (‘core’ aldehydes). These aldehydes induce endothelial cells to produce monocyte chemotactic factors and enhance monocyte–endothelium adhesion. They also serve as ligands of scavenger recepto...

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Bibliografiske detaljer
Main Authors: Spite, Matthew, Baba, Shahid P., Ahmed, Yonis, Barski, Oleg A., Nijhawan, Kanchan, Petrash, J. Mark, Bhatnagar, Aruni, Srivastava, Sanjay
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925154/
https://ncbi.nlm.nih.gov/pubmed/17381426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061743
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