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Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes

Phospholipid oxidation generates several bioactive aldehydes that remain esterified to the glycerol backbone (‘core’ aldehydes). These aldehydes induce endothelial cells to produce monocyte chemotactic factors and enhance monocyte–endothelium adhesion. They also serve as ligands of scavenger recepto...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Spite, Matthew, Baba, Shahid P., Ahmed, Yonis, Barski, Oleg A., Nijhawan, Kanchan, Petrash, J. Mark, Bhatnagar, Aruni, Srivastava, Sanjay
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925154/
https://ncbi.nlm.nih.gov/pubmed/17381426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061743
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