Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes

Phospholipid oxidation generates several bioactive aldehydes that remain esterified to the glycerol backbone (‘core’ aldehydes). These aldehydes induce endothelial cells to produce monocyte chemotactic factors and enhance monocyte–endothelium adhesion. They also serve as ligands of scavenger recepto...

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Autors principals: Spite, Matthew, Baba, Shahid P., Ahmed, Yonis, Barski, Oleg A., Nijhawan, Kanchan, Petrash, J. Mark, Bhatnagar, Aruni, Srivastava, Sanjay
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925154/
https://ncbi.nlm.nih.gov/pubmed/17381426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061743
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