ALDOSE REDUCTASE PROTECTS AGAINST EARLY ATHEROSCLEROTIC LESION FORMATION IN APO E - NULL MICE

RATIONALE: Atherosclerotic lesion formation is associated with the accumulation of oxidized lipids. Products of lipid oxidation, particularly aldehydes, stimulate cytokine production and enhance monocyte adhesion, however their contribution to atherosclerotic lesion formation remains unclear. OBJECT...

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Autors principals: Srivastava, Sanjay, Vladykovskaya, Elena, Barski, Oleg A., Spite, Matthew, Kaiserova, Karin, Petrash, J. Mark, Chung, Stephen S, Hunt, Greg, Dawn, Buddhadeb, Bhatnagar, Aruni
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548455/
https://ncbi.nlm.nih.gov/pubmed/19729598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.200568
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