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Role of Aldose Reductase in the Metabolism and Detoxification of Carnosine-Acrolein Conjugates
Oxidation of unsaturated lipids generates reactive aldehydes that accumulate in tissues during inflammation, ischemia, or aging. These aldehydes form covalent adducts with histidine-containing dipeptides such as carnosine and anserine, which are present in high concentration in skeletal muscle, hear...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784727/ https://ncbi.nlm.nih.gov/pubmed/23928303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.504753 |
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