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Postischemic Deactivation of Cardiac Aldose Reductase: ROLE OF GLUTATHIONE S-TRANSFERASE P AND GLUTAREDOXIN IN REGENERATION OF REDUCED THIOLS FROM SULFENIC ACIDS
Aldose reductase (AR) is a multifunctional enzyme that catalyzes the reduction of glucose and lipid peroxidation-derived aldehydes. During myocardial ischemia, the activity of AR is increased due to the oxidation of its cysteine residues to sulfenic acids. It is not known, however, whether the activ...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924019/ https://ncbi.nlm.nih.gov/pubmed/20538586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146423 |
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