Genome Plasticity of agr-Defective Staphylococcus aureus during Clinical Infection

Therapy for bacteremia caused by Staphylococcus aureus is often ineffective, even when treatment conditions are optimal according to experimental protocols. Adapted subclones, such as those bearing mutations that attenuate agr-mediated virulence activation, are associated with persistent infection a...

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Dades bibliogràfiques
Publicat a:Infect Immun
Autors principals: Altman, Deena R., Sullivan, Mitchell J., Chacko, Kieran I., Balasubramanian, Divya, Pak, Theodore R., Sause, William E., Kumar, Krishan, Sebra, Robert, Deikus, Gintaras, Attie, Oliver, Rose, Hannah, Lewis, Martha, Fulmer, Yi, Bashir, Ali, Kasarskis, Andrew, Schadt, Eric E., Richardson, Anthony R., Torres, Victor J., Shopsin, Bo, van Bakel, Harm
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Molecular Genomics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204747/
https://ncbi.nlm.nih.gov/pubmed/30061376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00331-18
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