Whole-Genome Sequencing Identifies Emergence of a Quinolone Resistance Mutation in a Case of Stenotrophomonas maltophilia Bacteremia

Whole-genome sequences for Stenotrophomonas maltophilia serial isolates from a bacteremic patient before and after development of levofloxacin resistance were assembled de novo and differed by one single-nucleotide variant in smeT, a repressor for multidrug efflux operon smeDEF. Along with sequenced...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Pak, Theodore R., Altman, Deena R., Attie, Oliver, Sebra, Robert, Hamula, Camille L., Lewis, Martha, Deikus, Gintaras, Newman, Leah C., Fang, Gang, Hand, Jonathan, Patel, Gopi, Wallach, Fran, Schadt, Eric E., Huprikar, Shirish, van Bakel, Harm, Kasarskis, Andrew, Bashir, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604410/
https://ncbi.nlm.nih.gov/pubmed/26324280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01723-15
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