Genetic Basis of Emerging Vancomycin, Linezolid, and Daptomycin Heteroresistance in a Case of Persistent Enterococcus faecium Bacteremia

Whole-genome sequencing was used to examine a persistent Enterococcus faecium bacteremia that acquired heteroresistance to three antibiotics in response to prolonged multidrug therapy. A comparison of the complete genomes before and after each change revealed the emergence of known resistance determ...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Chacko, Kieran I., Sullivan, Mitchell J., Beckford, Colleen, Altman, Deena R., Ciferri, Brianne, Pak, Theodore R., Sebra, Robert, Kasarskis, Andrew, Hamula, Camille L., van Bakel, Harm
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913925/
https://ncbi.nlm.nih.gov/pubmed/29339387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02007-17
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