Genome Plasticity of agr-Defective Staphylococcus aureus during Clinical Infection

Therapy for bacteremia caused by Staphylococcus aureus is often ineffective, even when treatment conditions are optimal according to experimental protocols. Adapted subclones, such as those bearing mutations that attenuate agr-mediated virulence activation, are associated with persistent infection a...

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Udgivet i:Infect Immun
Main Authors: Altman, Deena R., Sullivan, Mitchell J., Chacko, Kieran I., Balasubramanian, Divya, Pak, Theodore R., Sause, William E., Kumar, Krishan, Sebra, Robert, Deikus, Gintaras, Attie, Oliver, Rose, Hannah, Lewis, Martha, Fulmer, Yi, Bashir, Ali, Kasarskis, Andrew, Schadt, Eric E., Richardson, Anthony R., Torres, Victor J., Shopsin, Bo, van Bakel, Harm
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Molecular Genomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204747/
https://ncbi.nlm.nih.gov/pubmed/30061376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00331-18
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