Genome Plasticity of agr-Defective Staphylococcus aureus during Clinical Infection

Therapy for bacteremia caused by Staphylococcus aureus is often ineffective, even when treatment conditions are optimal according to experimental protocols. Adapted subclones, such as those bearing mutations that attenuate agr-mediated virulence activation, are associated with persistent infection a...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Altman, Deena R., Sullivan, Mitchell J., Chacko, Kieran I., Balasubramanian, Divya, Pak, Theodore R., Sause, William E., Kumar, Krishan, Sebra, Robert, Deikus, Gintaras, Attie, Oliver, Rose, Hannah, Lewis, Martha, Fulmer, Yi, Bashir, Ali, Kasarskis, Andrew, Schadt, Eric E., Richardson, Anthony R., Torres, Victor J., Shopsin, Bo, van Bakel, Harm
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
Assuntos:
Molecular Genomics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204747/
https://ncbi.nlm.nih.gov/pubmed/30061376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00331-18
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