Genome Plasticity of agr-Defective Staphylococcus aureus during Clinical Infection

Therapy for bacteremia caused by Staphylococcus aureus is often ineffective, even when treatment conditions are optimal according to experimental protocols. Adapted subclones, such as those bearing mutations that attenuate agr-mediated virulence activation, are associated with persistent infection a...

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Vydáno v:Infect Immun
Hlavní autoři: Altman, Deena R., Sullivan, Mitchell J., Chacko, Kieran I., Balasubramanian, Divya, Pak, Theodore R., Sause, William E., Kumar, Krishan, Sebra, Robert, Deikus, Gintaras, Attie, Oliver, Rose, Hannah, Lewis, Martha, Fulmer, Yi, Bashir, Ali, Kasarskis, Andrew, Schadt, Eric E., Richardson, Anthony R., Torres, Victor J., Shopsin, Bo, van Bakel, Harm
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Molecular Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204747/
https://ncbi.nlm.nih.gov/pubmed/30061376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00331-18
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