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Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences

BACKGROUND: The study of ancient DNA is hampered by degradation, resulting in short DNA fragments. Advances in laboratory methods have made it possible to retrieve short DNA fragments, thereby improving access to DNA preserved in highly degraded, ancient material. However, such material contains lar...

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Vydáno v:BMC Biol
Hlavní autoři: de Filippo, Cesare, Meyer, Matthias, Prüfer, Kay
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202837/
https://ncbi.nlm.nih.gov/pubmed/30359256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0581-9
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