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Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences

BACKGROUND: The study of ancient DNA is hampered by degradation, resulting in short DNA fragments. Advances in laboratory methods have made it possible to retrieve short DNA fragments, thereby improving access to DNA preserved in highly degraded, ancient material. However, such material contains lar...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: de Filippo, Cesare, Meyer, Matthias, Prüfer, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202837/
https://ncbi.nlm.nih.gov/pubmed/30359256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0581-9
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