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Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences

BACKGROUND: The study of ancient DNA is hampered by degradation, resulting in short DNA fragments. Advances in laboratory methods have made it possible to retrieve short DNA fragments, thereby improving access to DNA preserved in highly degraded, ancient material. However, such material contains lar...

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Publicat a:BMC Biol
Autors principals: de Filippo, Cesare, Meyer, Matthias, Prüfer, Kay
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202837/
https://ncbi.nlm.nih.gov/pubmed/30359256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0581-9
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