Computational challenges in the analysis of ancient DNA

High-throughput sequencing technologies have opened up a new avenue for studying extinct organisms. Here we identify and quantify biases introduced by particular characteristics of ancient DNA samples. These analyses demonstrate the importance of closely related genomic sequence for correctly identi...

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Main Authors: Prüfer, Kay, Stenzel, Udo, Hofreiter, Michael, Pääbo, Svante, Kelso, Janet, Green, Richard E
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Method
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898072/
https://ncbi.nlm.nih.gov/pubmed/20441577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-5-r47
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