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Computational challenges in the analysis of ancient DNA

High-throughput sequencing technologies have opened up a new avenue for studying extinct organisms. Here we identify and quantify biases introduced by particular characteristics of ancient DNA samples. These analyses demonstrate the importance of closely related genomic sequence for correctly identi...

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Detalhes bibliográficos
Main Authors: Prüfer, Kay, Stenzel, Udo, Hofreiter, Michael, Pääbo, Svante, Kelso, Janet, Green, Richard E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898072/
https://ncbi.nlm.nih.gov/pubmed/20441577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-5-r47
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