Computational challenges in the analysis of ancient DNA

High-throughput sequencing technologies have opened up a new avenue for studying extinct organisms. Here we identify and quantify biases introduced by particular characteristics of ancient DNA samples. These analyses demonstrate the importance of closely related genomic sequence for correctly identi...

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Autors principals: Prüfer, Kay, Stenzel, Udo, Hofreiter, Michael, Pääbo, Svante, Kelso, Janet, Green, Richard E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898072/
https://ncbi.nlm.nih.gov/pubmed/20441577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-5-r47
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