Patterns of damage in genomic DNA sequences from a Neandertal

High-throughput direct sequencing techniques have recently opened the possibility to sequence genomes from Pleistocene organisms. Here we analyze DNA sequences determined from a Neandertal, a mammoth, and a cave bear. We show that purines are overrepresented at positions adjacent to the breaks in th...

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Bibliografiske detaljer
Main Authors: Briggs, Adrian W., Stenzel, Udo, Johnson, Philip L. F., Green, Richard E., Kelso, Janet, Prüfer, Kay, Meyer, Matthias, Krause, Johannes, Ronan, Michael T., Lachmann, Michael, Pääbo, Svante
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976210/
https://ncbi.nlm.nih.gov/pubmed/17715061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704665104
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