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Activity of Aromathecins against African Trypanosomes

African sleeping sickness is responsible for thousands of deaths annually, and new therapeutics are needed. This study evaluated aromathecins, experimental inhibitors of mammalian topoisomerase IB, against Trypanosoma brucei African trypanosomes. The compounds had selectively toxic antiparasitic pot...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Nenortas, Nathaniel P., Cinelli, Maris A., Morrell, Andrew E., Cushman, Mark, Shapiro, Theresa A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201061/
https://ncbi.nlm.nih.gov/pubmed/30104277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00786-18
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