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The histone demethylase LSD1 regulates B cell proliferation and plasmablast differentiation(1)

B cells undergo epigenetic remodeling as they differentiate into antibody-secreting cells. LSD1 is a histone demethylase known to decommission active enhancers and cooperate with the antibody-secreting cell master regulatory transcription factor Blimp-1. The contribution of LSD1 to ASC formation is...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Haines, Robert R., Barwick, Benjamin G., Scharer, Christopher D., Majumder, Parimal, Randall, Troy D., Boss, Jeremy M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200601/
https://ncbi.nlm.nih.gov/pubmed/30232138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800952
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