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Histone Demethylase LSD1 Regulates Neural Stem Cell Proliferation

Lysine-specific demethylase 1 (LSD1) functions as a transcriptional coregulator by modulating histone methylation. Its role in neural stem cells has not been studied. We show here for the first time that LSD1 serves as a key regulator of neural stem cell proliferation. Inhibition of LSD1 activity or...

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Hlavní autoři: Sun, GuoQiang, Alzayady, Kamil, Stewart, Richard, Ye, Peng, Yang, Su, Li, Wendong, Shi, Yanhong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849468/
https://ncbi.nlm.nih.gov/pubmed/20123967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01116-09
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