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The histone demethylase LSD1 regulates B cell proliferation and plasmablast differentiation(1)
B cells undergo epigenetic remodeling as they differentiate into antibody-secreting cells. LSD1 is a histone demethylase known to decommission active enhancers and cooperate with the antibody-secreting cell master regulatory transcription factor Blimp-1. The contribution of LSD1 to ASC formation is...
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| Udgivet i: | J Immunol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6200601/ https://ncbi.nlm.nih.gov/pubmed/30232138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800952 |
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