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Protein tyrosine phosphatase PTPN22 regulates LFA-1 dependent Th1 responses
A missense C1858T single nucleotide polymorphism within PTPN22 is a strong genetic risk factor for the development of multiple autoimmune diseases. PTPN22 encodes a protein tyrosine phosphatase that negatively regulates immuno-receptor proximal Src and Syk family kinases. Notably, PTPN22 negatively...
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| Publicado no: | J Autoimmun |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Academic Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6198113/ https://ncbi.nlm.nih.gov/pubmed/30054208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2018.07.008 |
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