New insights into the T cell synapse from single molecule techniques

Por Dustin, Michael L., Depoil, David
Publicado em 2011

Agile CD22 nanoclusters run rings around fenced BCR

Por Depoil, David, Dustin, Michael L
Publicado no EMBO J (2016)

Force and affinity in ligand discrimination by the TCR

Por Depoil, David, Dustin, Michael L.
Publicado no Trends Immunol (2014)

Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses

Por Wiedemann, Aurelie, Depoil, David, Faroudi, Mustapha, Valitutti, Salvatore
Publicado em 2006

Dynamic cortical actin remodeling by ERM proteins controls BCR microcluster organization and integrity

Por Treanor, Bebhinn, Depoil, David, Bruckbauer, Andreas, Batista, Facundo D.
Publicado em 2011

Effects of Intracellular Calcium and Actin Cytoskeleton on TCR Mobility Measured by Fluorescence Recovery

Por Dushek, Omer, Mueller, Sabina, Soubies, Sebastien, Depoil, David, Caramalho, Iris, Coombs, Daniel, Valitutti, Salvatore
Publicado em 2008

Bifunctional nanoarrays for probing the immune response at the single-molecule level

Por Cai, Haogang, Depoil, David, Palma, Matteo, Sheetz, Michael P., Dustin, Michael L., Wind, Shalom J.
Publicado em 2013

Molecular Occupancy of Nanodot Arrays

Por Cai, Haogang, Wolfenson, Haguy, Depoil, David, Dustin, Michael L., Sheetz, Michael P., Wind, Shalom J.
Publicado no ACS Nano (2016)

Imaging of HIV-1 Envelope-induced Virological Synapse and Signaling on Synthetic Lipid Bilayers

Por Prins, Kathleen C., Vasiliver-Shamis, Gaia, Cammer, Michael, Depoil, David, Dustin, Michael L., Hioe, Catarina E.
Publicado em 2012

Nanoscale ligand spacing influences receptor triggering in T cells and NK cells

Por Delcassian, Derfogail, Depoil, David, Rudnicka, Dominika, Liu, Mengling, Davis, Daniel M., Dustin, Michael L., Dunlop, Iain E.
Publicado no Nano Lett (2013)

Phospholipase C-γ2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen

Por Weber, Michele, Treanor, Bebhinn, Depoil, David, Shinohara, Hisaaki, Harwood, Naomi E., Hikida, Masaki, Kurosaki, Tomohiro, Batista, Facundo D.
Publicado em 2008

Phospholipase C-γ2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen

Por Weber, Michele, Treanor, Bebhinn, Depoil, David, Shinohara, Hisaaki, Harwood, Naomi E., Hikida, Masaki, Kurosaki, Tomohiro, Batista, Facundo D.
Publicado em 2008

The Membrane Skeleton Controls Diffusion Dynamics and Signaling through the B Cell Receptor

Por Treanor, Bebhinn, Depoil, David, Gonzalez-Granja, Aitor, Barral, Patricia, Weber, Michele, Dushek, Omer, Bruckbauer, Andreas, Batista, Facundo D.
Publicado em 2010

T Cell Activation is Determined by the Number of Presented Antigens

Por Deeg, Janosch, Axmann, Markus, Matic, Jovana, Liapis, Anastasia, Depoil, David, Afrose, Jehan, Curado, Silvia, Dustin, Michael L., Spatz, Joachim P.
Publicado em 2013

Durable Interactions of T Cells with T Cell Receptor Stimuli in the Absence of a Stable Immunological Synapse

Por Mayya, Viveka, Judokusumo, Edward, Abu Shah, Enas, Peel, Christopher G., Neiswanger, Willie, Depoil, David, Blair, David A., Wiggins, Chris H., Kam, Lance C., Dustin, Michael L.
Publicado no Cell Rep (2018)

Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway

Por Kumari, Sudha, Depoil, David, Martinelli, Roberta, Judokusumo, Edward, Carmona, Guillaume, Gertler, Frank B, Kam, Lance C, Carman, Christopher V, Burkhardt, Janis K, Irvine, Darrell J, Dustin, Michael L
Publicado no eLife (2015)

Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells

Por Céspedes, Pablo F., Bueno, Susan M., Ramírez, Bruno A., Gomez, Roberto S., Riquelme, Sebastián A., Palavecino, Christian E., Mackern-Oberti, Juan Pablo, Mora, Jorge E., Depoil, David, Sacristán, Catarina, Cammer, Michael, Creneguy, Alison, Nguyen, Tuan H., Riedel, Claudia A., Dustin, Michael L., Kalergis, Alexis M.
Publicado em 2014

Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism

Por Zanin-Zhorov, Alexandra, Weiss, Jonathan M., Nyuydzefe, Melanie S., Chen, Wei, Scher, Jose U., Mo, Rigen, Depoil, David, Rao, Nishta, Liu, Ben, Wei, Jianlu, Lucas, Sarah, Koslow, Matthew, Roche, Maria, Schueller, Olivier, Weiss, Sara, Poyurovsky, Masha V., Tonra, James, Hippen, Keli L., Dustin, Michael L., Blazar, Bruce R., Liu, Chuan-ju, Waksal, Samuel D.
Publicado no Proc Natl Acad Sci U S A (2014)