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Force and affinity in ligand discrimination by the TCR
T cell recognition of antigen is a physical process that requires formation of a cell-cell junction that is rich in active force generation. Recently, a biomolecular force probe was used to examine how the TCR-pMHC interaction responds to force and the consequences of force dependent interactions fo...
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| Pubblicato in: | Trends Immunol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617748/ https://ncbi.nlm.nih.gov/pubmed/25466309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2014.10.007 |
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