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Ligand recognition by the γδ TCR and discrimination between homeostasis and stress conditions

T lymphocytes comprise cells expressing either an αβ or a γδ TCR. The riddle how αβ TCRs are triggered by specific peptides presented in the context of MHC was elucidated some time ago. In contrast, the mechanisms that underlie antigen recognition by γδ TCRs are still baffling the scientific communi...

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Publicat a:Cell Mol Immunol
Autors principals: Deseke, Malte, Prinz, Immo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608190/
https://ncbi.nlm.nih.gov/pubmed/32709926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-0503-y
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