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Low-Affinity Ligands for the TCR Drive Proliferation of Mature CD8(+) T Cells in Lymphopenic Hosts

In the absence of thymic emigration, the peripheral T cell pool is maintained by division of mature lymphocytes. We have examined the molecular interactions required for peripheral CD8(+) T cell expansion in lymphopenic mice without conventional antigenic stimulation. Expansion of CD8(+) T cells in...

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Detalhes bibliográficos
Main Authors: Goldrath, Ananda W., Bevan, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789737/
https://ncbi.nlm.nih.gov/pubmed/10485653
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