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Antibody affinity maturation: the role of CD8+ cells.

The cellular control of antibody affinity maturation has been studied in mice genetically selected for their failure to demonstrate an increase in affinity following immunization (low-affinity N/M mice). Depletion of CD8+ cells in low N/M mice by thymectomy and/or anti-CD8 antibody treatment resulte...

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Autors principals: Holland, G P, Steward, M W
Format: Artigo
Idioma:Inglês
Publicat: 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534833/
https://ncbi.nlm.nih.gov/pubmed/2532994
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