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The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens
A C1858T single nucleotide polymorphism within PTPN22 (which encodes PTPN22(R620W)) is associated with an enhanced susceptibility to multiple autoimmune diseases including type 1 diabetes and rheumatoid arthritis. Many of the associated autoimmune diseases have an autoantibody component to their pat...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6107551/ https://ncbi.nlm.nih.gov/pubmed/30139951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31179-x |
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