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Palladium-Catalyzed Enantioselective Csp(3)–Csp(3) Cross-Coupling for the Synthesis of (Poly)fluorinated Chiral Building Blocks
A general method for the enantioselective synthesis of carbo- and heterocyclic carbonyl compounds bearing fluorinated α-tetrasubstituted stereocenters using palladium-catalyzed decarboxylative allylic alkylation is described. The stereoselective Csp(3) –Csp(3) cross-coupling reaction delivers five-...
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| Gepubliceerd in: | Org Lett |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6192028/ https://ncbi.nlm.nih.gov/pubmed/30183315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b02369 |
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